About 8 a.m. on September 17, 1991, Norfolk Southern (NS) train 277, en route west from Fort Wayne, Indiana, to Chicago, Illinois, struck eastbound train 629 head-on at milepost (MP) 455 1 near Knox, Indiana. The accident occurred on the main track west of the Knox siding. One locomotive and four cars of train 277 and three locomotives and five cars of train 629 derailed. The engineer of train 277 was killed, and the conductor sustained serious injuries. The student engineer of train 277 and all three crewmembers on train 629 sustained minor injuries.